Purpose: Society’s reliance on information, communication, computing and cyberinfrastructure in all aspects of daily life increases more and more each day. Innovations in these areas are now central to how we work, live, learn, communicate, shop, travel, socialize and conduct scientific research – a testament to the tremendous progress in computer and information science and engineering in the last 50 years fueled by strong research breakthroughs in all areas including artificial intelligence, hardware, networking, robotics, software, systems, and theory. The unprecedented growth and reach of information, communication, computing and cyberinfrastructure, and the constantly increasing demand for innovations and novel applications presents new fundamental and translational research challenges that need to be addressed. The information, communication, computing and cyberinfrastructure research community needs to stay ahead of the curve in this constantly evolving landscape.